New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species

被引：33

作者：

Meragelman, KM ^{[1
]}

McKee, TC ^{[1
]}

Boyd, MR ^{[1
]}

机构：

[1] NCI, Frederick Canc Res & Dev Ctr, Lab Drug Discovery Res & Dev, Div Basic Sci, Frederick, MD 21702 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 03期

关键词：

D O I：

10.1021/np000478g

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new isomalabaricane triterpenes, 29-hydroxystelliferin E (1), 29-hydroxystelliferin A (2), and stelliferin G (3), together with the known triterpene 3-epi-29-tiydroxystelliferin E (4), were isolated from the organic extract of the sponge Jaspis sp. collected in the South Pacific. All the compounds isolated showed antiproliferative activity against melanoma cells (MALME-3M).

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页码：389 / 392

页数：4

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