Biomedical applications of hydrogels: A review of patents and commercial products

被引：1868

作者：

Calo, Enrica ^{[1
]}

Khutoryanskiy, Vitaliy V. ^{[1
]}

机构：

[1] Univ Reading, Sch Pharm, Reading RG6 6AD, Berks, England

来源：

EUROPEAN POLYMER JOURNAL | 2015年 / 65卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

Hydrogels; Contact lenses; Drug delivery; Wound dressings; Biomaterials; DRUG-DELIVERY; CONTROLLED-RELEASE; BIODEGRADABLE HYDROGELS; OXYGEN PERMEABILITY; REFRACTIVE-INDEX; CONTACT-LENSES; POLYMERS; RADIATION; SYSTEMS; DESIGN;

D O I：

10.1016/j.eurpolymj.2014.11.024

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

Hydrogels have become very popular due to their unique properties such as high water content, softness, flexibility and biocompatibility. Natural and synthetic hydrophilic polymers can be physically or chemically cross-linked in order to produce hydrogels. Their resemblance to living tissue opens up many opportunities for applications in biomedical areas. Currently, hydrogels are used for manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery systems and wound dressings. This review provides an analysis of their main characteristics and biomedical applications. From Wichterle's pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments. (C) 2014 The Authors. Published by Elsevier Ltd.

引用

页码：252 / 267

页数：16

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