General principles of migraine management: The changing role of prevention

被引:55
作者
Loder, E
Biondi, D
机构
[1] Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Headache Program, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Pain Management Program, Boston, MA 02114 USA
来源
HEADACHE | 2005年 / 45卷
关键词
migraine; prophylactic; antiepileptic; neuromodulators; topiramate; prevention; neuroplasticity;
D O I
10.1111/j.1526-4610.2005.4501002.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The role of preventive treatment in the management of migraine must be reassessed. Many patients who would benefit from preventive therapy do not receive it, and many might benefit from earlier and more aggressive use of preventive therapy. Physicians who treat migraine have long recognized that a subset of patients with episodic migraine evolve to chronic forms of the disorder that are difficult to treat and have a poor outcome. This article reviews the evidence for current and emerging prophylactic migraine treatment and raises the possibility that timely use of prophylactic treatment might modify or prevent the transformation to chronic migraine and the extreme disability that characterizes a small but significant subset of the migraine population. Along with aggressive treatment of the acute pain and other symptoms of migraine, prevention of progression to severe forms of this disorder will increasingly be a focus and goal of the treatment.
引用
收藏
页码:S33 / S47
页数:15
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