Periostin and myocardial repair, regeneration, and recovery

被引：57

作者：

Dorn, Gerald W., II ^{[1
]}

机构：

[1] Univ Cincinnati, Ctr Mol Cardiovasc Res, Cincinnati, OH 45221 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2007年 / 357卷 / 15期

关键词：

D O I：

10.1056/NEJMcibr074816

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In rats with myocardial infarction, the boosting of levels of cardiac periostin - a matrix molecule derived from fibroblasts - was associated with increased DNA synthesis by cardiomyocytes, enhanced angiogenesis, and improved cardiac function. Copyright © 2007 Massachusetts Medical Society. All Rights Reserved.

引用

页码：1552 / 1554

页数：3

共 5 条

[1] Myocyte renewal and ventricular remodelling [J].

Anversa, P ;

Nadal-Ginard, B .

NATURE, 2002, 415 (6868) :240-243

[2]

Kudo Y, 2007, HISTOL HISTOPATHOL, V22, P1167, DOI 10.14670/HH-22.1167

[3] Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair [J].

Kuhn, Bernhard ;

del Monte, Federica ;

Hajjar, Roger J. ;

Chang, Yuh-Shin ;

Lebeche, Djamel ;

Arab, Shima ;

Keating, Mark T. .

NATURE MEDICINE, 2007, 13 (08) :962-969

[4] Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling [J].

Oka, Toru ;

Xu, Jian ;

Kaiser, Robert A. ;

Melendez, Jaime ;

Hambleton, Michael ;

Sargent, Michelle A. ;

Lorts, Angela ;

Brunskill, Eric W. ;

Dorn, Gerald W., II ;

Conway, Simon J. ;

Aronow, Bruce J. ;

Robbins, Jeffrey ;

Molkentin, Jeffery D. .

CIRCULATION RESEARCH, 2007, 101 (03) :313-321

[5] LEFT-VENTRICULAR END-SYSTOLIC VOLUME AS THE MAJOR DETERMINANT OF SURVIVAL AFTER RECOVERY FROM MYOCARDIAL-INFARCTION [J].

WHITE, HD ;

NORRIS, RM ;

BROWN, MA ;

BRANDT, PWT ;

WHITLOCK, RML ;

WILD, CJ .

CIRCULATION, 1987, 76 (01) :44-51

← 1 →