The anorexia of aging

被引：62

作者：

Chapman, Ian McPhee ^{[1
]}

机构：

[1] Univ Adelaide, Royal Adelaide Hosp, Dept Med, Adelaide, SA 5000, Australia

来源：

CLINICS IN GERIATRIC MEDICINE | 2007年 / 23卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.cger.2007.06.001

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Undernutrition is common in the elderly, particularly those in nursing homes and other institutions. It is associated with substantial adverse effects. The age-associated physiologic reduction in appetite and food intake, which has been termed "the anorexia of aging," contributes to the development of pathologic anorexia and undernutrition. This article reviews age-related changes to appetite, food intake, and body composition; undernutrition in the elderly; and the factors contributing to physiologic and pathologic anorexia and undernutrition.

引用

页码：735 / +

页数：23

共 91 条

[1] Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery [J].

Amory, JK ;

Chansky, HA ;

Chansky, KL ;

Camuso, MR ;

Hoey, CT ;

Anawalt, BD ;

Matsumoto, AM ;

Bremner, WJ .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (10) :1698-1701

[2] Testosterone improves rehabilitation outcomes in ill older men [J].

Bakhshi, V ;

Elliott, M ;

Gentili, A ;

Godschalk, M ;

Mulligan, T .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (05) :550-553

[3]

Baraniuk JN, 2000, J CFS, V7, P3

[4] Gut hormone PYY3-36 physiologically inhibits food intake [J].

Batterham, RL ;

Cowley, MA ;

Small, CJ ;

Herzog, H ;

Cohen, MA ;

Dakin, CL ;

Wren, AM ;

Brynes, AE ;

Low, MJ ;

Ghatei, MA ;

Cone, RD ;

Bloom, SR .

NATURE, 2002, 418 (6898) :650-654

[5] Inhibition of food intake in obese subjects by peptide YY3-36 [J].

Batterham, RL ;

Cohen, MA ;

Ellis, SM ;

Le Roux, CW ;

Withers, DJ ;

Frost, GS ;

Ghatei, MA ;

Bloom, SR .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (10) :941-948

[6] Age-related changes in sex hormones affect the sex difference in serum leptin independently of changes in body fat [J].

Baumgartner, RN ;

Waters, DL ;

Morley, JE ;

Patrick, P ;

Montoya, GD ;

Garry, PJ .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1999, 48 (03) :378-384

[7] Fat and protein redistribution with aging:: metabolic considerations [J].

Beaufrère, B ;

Morio, B .

EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2000, 54 (Suppl 3) :S48-S53

[8] Loxiglumide, a CCK-A receptor antagonist, stimulates calorie intake and hunger feelings in humans [J].

Beglinger, C ;

Degen, L ;

Matzinger, D ;

D'Amato, M ;

Drewe, J .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2001, 280 (04) :R1149-R1154

[9] Reduced feeding response to neuropeptide Y in senescent Fischer 344 rats [J].

Blanton, CA ;

Horwitz, BA ;

Blevins, JE ;

Hamilton, JS ;

Hernandez, EJ ;

McDonald, RB .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2001, 280 (04) :R1052-R1060

[10] PYY3-36 as an anti-obesity drug target [J].

Boggiano, MM ;

Chandler, PC ;

Oswald, KD ;

Rodgers, RJ ;

Blundell, JE ;

Ishii, Y ;

Beattie, AH ;

Holch, P ;

Allison, DB ;

Schindler, M ;

Arndt, K ;

Rudolf, K ;

Mark, M ;

Schoelch, C ;

Joost, HG ;

Klaus, S ;

Thöne-Reineke, C ;

Benoit, SC ;

Seeley, RJ ;

Beck-Sickinger, AG ;

Koglin, N ;

Raun, K ;

Madsen, K ;

Wulff, BS ;

Stidsen, CE ;

Birringer, M ;

Kreuzer, OJ ;

Deng, XY ;

Whitcomb, DC ;

Halem, H ;

Taylor, J ;

Dong, J ;

Datta, R ;

Culler, M ;

Ortmann, S ;

Castañeda, TR ;

Tschöp, M .

OBESITY REVIEWS, 2005, 6 (04) :307-322

← 1 2 3 4 5 6 7 8 9 10 →