Neuronal differentiation: Proneural genes inhibit gliogenesis

被引：34

作者：

Morrison, SJ

机构：

[1] Univ Michigan, Howard Hughes Med Inst, Dept Internal Med, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Howard Hughes Med Inst, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(01)00191-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Proneural basic helix-loop-helix transcription factors such as Neurogenin are activators of neuronal gene expression. Recent studies show they reinforce neuronal differentiation by also inhibiting the expression of glial genes, and are required in vivo to prevent premature and excessive gliogenesis.

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收藏

页码：R349 / R351

页数：3

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