Regioselective alkylation of aromatic aldimines and ketimines via C-H bond activation by a rhodium catalyst

被引：18

作者：

Lim, YG

Han, JS

Koo, BT

Kang, JB

机构：

[1] Agcy Def Dev, Taejon 305600, South Korea

[2] Hanbat Natl Univ, Dept Ind Chem, Taejon, South Korea

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2004年 / 209卷 / 1-2期

关键词：

alkylation; C-C bond formation; rhodium catalyst; aldimines; ketimines;

D O I：

10.1016/j.molcata.2003.08.019

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The aldimines and ketimines reacted with alkenes under a rhodium catalyst [Rh(coe)(2)Cl](2) and Cy3P to give mainly the double alkylated products with moderate to high yields. The aldimines bearing H, p-CH3O, p-CH3, p-Cl, p-F, p-CF3 and o-CH3 groups have high reactivities, but m-CH3O, m-Cl and m-F exhibit moderate reactivities. However, o-Cl, o-NO2 and p-NO2 groups did not work. The ketimine 9 gave the mono-alkylated products predominantly. 1-Naphthyl and heteroaromatic aldimines showed good regioselectivities. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：41 / 49

页数：9

共 49 条

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