Stimulating activity of Chinese medicinal herbs on human lymphocytes in vitro

被引：120

作者：

Shan, BE ^{[1
]}

Yoshida, Y ^{[1
]}

Sugiura, T ^{[1
]}

Yamashita, U ^{[1
]}

机构：

[1] Univ Occupat & Environm Hlth, Sch Med, Dept Immunol, Yahatanishiku, Kitakyushu, Fukuoka 8078555, Japan

来源：

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY | 1999年 / 21卷 / 03期

关键词：

Chinese medicinal herb; T-cell; B-cell; monocyte; tumor immunity;

D O I：

10.1016/S0192-0561(98)00074-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The effects of eight kinds of Chinese medicinal herbs (CMH) on human lymphocytes was studied in vitro. The extract of Cinnamomum cassia presl markedly stimulated human lymphocytes to proliferate. Codonopsis pilosula, Oldenlandia diffusa and Rhizoma typhonii weakly stimulated. These extracts enhanced cytotoxic T-lymphocyte (CTL) activity, but failed to enhance natural killer (NK)-cell activity. The extracts of these CMHs have stimulatory effect on immunoglobulin (Ig) production by B-cells and interleukin(IL)-1 production by monocytes. These activities of Cinnamomum cassia pr esl extract are associated with glycoproteins, whose molecular weight was about 100 KDa. These results suggest that CMH extracts have a stimulating activity on human lymphocytes and these abilities could be used clinically for the treatment of diseases such as cancer. (C) 1999 International Society for Immunopharmacology. Published by Elsevier Science Ltd.

引用

页码：149 / 159

页数：11

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