Metadoxine in the treatment of acute and chronic alcoholism: A review

被引：57

作者：

Addolorato, G ^{[1
]}

Ancona, C ^{[1
]}

Capristo, E ^{[1
]}

Gasbarrini, G ^{[1
]}

机构：

[1] Catholic Univ Rome, Inst Internal Med, I-00168 Rome, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2003年 / 16卷 / 03期

关键词：

metadoxine; alcoholisin; acute and chronic alcohol intoxication;

D O I：

10.1177/039463200301600304

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Alcohol abuse and alcoholism are responsible for a wide variety of medical problems. The pharmacotherapeutic aspect of alcoholism includes the use of drugs, with different actions and objectives. Among them, metadoxine seems to be of interest. Metadoxine is able to accelerate the elimination of alcohol from the blood and tissues, to help restore the functional structure of the liver and to relieve neuro-psychological disorders associated with alcohol intoxication. Metadoxine also seems to be safe; in more than 15 years of post-marketing surveillance only minor aspecific and reversible events were monitored in patients exposed to the treatment. In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported.

引用

页码：207 / 214

页数：8

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