Microbial dehalogenases: enzymes recruited to convert xenobiotic substrates

被引：54

作者：

Copley, SD ^{[1
]}

机构：

[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1998年 / 2卷 / 05期

关键词：

D O I：

10.1016/S1367-5931(98)80092-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microbial dehalogenases are involved in the biodegradation of many important chlorinated pollutants. Some recent studies of haloalkane dehalogenase, dichloromethane dehalogenase, tetrachlorohydroquinone dehalogenase and perchloroethylene and trichloroethylene reductive dehalogenases have addressed the issue of recruitment and adaptation of proteins to dehalogenate novel substrates.

引用

页码：613 / 617

页数：5

共 38 条

[1] Genetic and biochemical characterization of the broad spectrum chlorobenzene dioxygenase from Burkholderia sp. strain PS12 - Dechlorination of 1,2,4,5-tetrachlorobenzene
Beil, S
Happe, B
Timmis, KN
Pieper, DH
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 247 (01): : 190 - 199
[2] Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 angstrom resolution: An enzyme catalyst generated via adaptive mutation
Benning, MM
Taylor, KL
Liu, RQ
Yang, G
Xiang, H
Wesenberg, G
DunawayMariano, D
Holden, HM
[J]. BIOCHEMISTRY, 1996, 35 (25) : 8103 - 8109
[3] BLOCKI FA, 1994, J BIOL CHEM, V269, P8826
[4] Cloning and nucleotide sequence of a D,L-haloalkanoic acid dehalogenase encoding gene from Alcaligenes xylosoxidans ssp denitrificans ABIV
Brokamp, A
Happe, B
Schmidt, FRJ
[J]. BIODEGRADATION, 1997, 7 (05) : 383 - 396
[5] STRUCTURAL AND FUNCTIONAL-CHARACTERIZATION OF THE MUTANT ESCHERICHIA-COLI GLUTAREDOXIN(C14-]S) AND ITS MIXED DISULFIDE WITH GLUTATHIONE
BUSHWELLER, JH
ASLUND, F
WUTHRICH, K
HOLMGREN, A
[J]. BIOCHEMISTRY, 1992, 31 (38) : 9288 - 9293
[6] COPLEY SD, ENZYMES ENZYME MECHA, V5
[7] CRYSTAL-STRUCTURE OF HALOALKANE DEHALOGENASE - AN ENZYME TO DETOXIFY HALOGENATED ALKANES
FRANKEN, SM
ROZEBOOM, HJ
KALK, KH
DIJKSTRA, BW
[J]. EMBO JOURNAL, 1991, 10 (06) : 1297 - 1302
[8] Gisi D, 1998, APPL ENVIRON MICROB, V64, P1194
[9] Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp YL - An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold
Hisano, T
Hata, Y
Fujii, T
Liu, JQ
Kurihara, T
Esaki, N
Soda, K
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (34) : 20322 - 20330
[10] KENNES C, 1995, EUR J BIOCHEM, V228, P403

← 1 2 3 4 →