The mannose receptor mediates the cellular immune response in human coccidioidomycosis

被引：19

作者：

Ampel, NM

Nelson, DK

Li, LJ

Dionne, SO

Lake, DF

Simmons, KA

Pappagianis, D

机构：

[1] Univ Arizona, Hlth Sci Ctr, Dept Med, Tucson, AZ USA

[2] Univ Arizona, Hlth Sci Ctr, Dept Microbiol & Immunol, Tucson, AZ USA

[3] Univ Arizona, Hlth Sci Ctr, Arizona Canc Ctr, Tucson, AZ USA

[4] So Arizona Vet Affairs Med Ctr, Med Serv, Tucson, AZ USA

[5] So Arizona Vet Affairs Med Ctr, Res Serv, Tucson, AZ USA

[6] Univ Calif Davis, Dept Microbiol & Immunol, Davis, CA 95616 USA

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 04期

关键词：

D O I：

10.1128/IAI.73.4.2554-2555.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interieukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

引用

页码：2554 / 2555

页数：2

共 14 条

[1] Delayed-type hypersensitivity, in vitro T-cell responsiveness and risk of active coccidioidomycosis among HIV-infected patients living in the coccidioidal endemic area [J].