Inclusion body myositis in twins

被引：26

作者：

Amato, AA

Robert, RT

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Med Neurol, San Antonio, TX 78284 USA

[2] Univ Miami, Sch Med, Coral Gables, FL 33124 USA

来源：

NEUROLOGY | 1998年 / 51卷 / 02期

关键词：

D O I：

10.1212/WNL.51.2.598

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM. The lack of inflammation on biopsy and the different ages at onset and patterns of muscle weakness distinguish s-IBM from h-IBM. We report twin brothers with the typical clinical and histologic features of s-IBM. The occurrence of s-IBM in these twins suggests the possibility of a genetic susceptibility to developing s-IBM.

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页码：598 / 600

页数：3

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