Griffipavixanthone, a novel cytotoxic bixanthone from Garcinia griffithii and G-pavifolia

被引：47

作者：

Xu, YJ

Cao, SG

Wu, XH

Lai, YH

Tan, BHK

Pereira, JT

Goh, SH

Venkatraman, G

Harrison, LJ

Sim, KY

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

[2] Natl Univ Singapore, Dept Pharmacol, Singapore 119260, Singapore

[3] Forest Res Ctr, Sandakan, Sabah, Malaysia

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(98)02007-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

A bioactivity-directed fractionation of the extracts of the Malaysian plant Garcinia pavifolia and a phytochemical study of G. griffithii led to the discovery of griffipavixanthone (1), a novel cytotoxic bixanthone with cyclized prenyl groups providing the xanthone-xanthone linkage. Spectroscopic data and preparation of methylated derivatives allowed for the complete structural elucidation of I. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9103 / 9106

页数：4

共 7 条

[1]

Cytotoxic caged tetraprenylated xanthonoids from Garcinia gaudichaudii (Guttiferae) [J].