Construction of spiro[pyrrolidine-3,3′-oxindoles] -: Recent applications to the synthesis of oxindole alkaloids

被引：1417

作者：

Marti, C ^{[1
]}

Carreira, EM ^{[1
]}

机构：

[1] ETH, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 2003卷 / 12期

关键词：

alkaloids; natural products; total synthesis; spiro compounds;

D O I：

10.1002/ejoc.200300050

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The spiro[pyrrolidine-3,3'-oxindole] ring system is found at the core of a number of alkaloids, which possess significant biological activity and are interesting, challenging targets for chemical synthesis. In the present review, we report on the different strategies for the synthesis of the spiro[pyrrolidine-3,3'-oxindole] ring system in the context of recent synthesis of coerulescine, horsfiline, elacomine, salacin, pteropodine, alstonisine, spirotryprostatin A and B, and strychnofoline. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

引用

收藏

页码：2209 / 2219

页数：11

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