There appears to be no natural explanation for the cosmological constant's small size within the framework of local relativistic field theories. We argue that the recently-discussed framework for which the observable universe is identified with a p-brane embedded within a higher-dimensional 'bulk' spacetime, has special properties that may help circumvent the obstacles to this understanding. This possibility arises partly due to several unique features of the brane proposal. These are: (1) the potential such models introduce for partially breaking supersymmetry, (2) the possibility of having low-energy degrees of freedom which are not observable to us because they are physically located on a different brane, (3) the fundamental scale may be much smaller than the Planck scale. Furthermore, although the resulting cosmological constant in the scenarios we outline need not be exactly zero, it may be suppressed relative to the mass splittings of supermultiplets by weak coupling constants of gravitational strength, in accord with cosmological observations. (C) 2000 Elsevier Science B.V. All rights reserved.