Molecular cloning and sequence determination of a novel aspartic proteinase from Antarctic fish

被引：18

作者：

Capasso, C

Riggio, M

Scudiero, R

Carginale, V

di Prisco, G

Kay, J

Kille, P

Parisi, E

机构：

[1] Inst Prot Biochem & Enzymol, I-80125 Naples, Italy

[2] Univ Naples Federico II, Dept Evolutionary & Comparat Biochem, I-80134 Naples, Italy

[3] Univ Wales, Sch Mol & Med Biosci, Cardiff CF1 3US, S Glam, Wales

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 1998年 / 1387卷 / 1-2期

关键词：

aspartic proteinase; cathepsin D; cathepsin E; (Antarctic fish);

D O I：

10.1016/S0167-4838(98)00136-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the present report, we describe a novel aspartic proteinase from the liver of two Antarctic fish species. The nucleotide sequences of the cDNA obtained from the two fishes show 90% identity with each other but only 58% identity with aspartic proteinases from other sources. Sequence analysis shows features for the Antarctic enzymes which are not present in related enzymes of other organisms. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：457 / 461

页数：5

共 14 条

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Barrett A, 1977, PROTEINASES MAMMALIA, P209

[2]

BRODELIUS PE, 1995, ADV EXP MED BIOL, V362, P255

[3] Molecular characterisation of ovarian cathepsin D in the rainbow trout, Oncorhynchus mykiss [J].