Use of viral vectors for vaccine production in plants

被引：124

作者：

Cañizares, MC ^{[1
]}

Nicholson, L ^{[1
]}

Lomonossoff, GP ^{[1
]}

机构：

[1] John Innes Ctr Plant Sci Res, Norwich NR4 7UH, Norfolk, England

来源：

IMMUNOLOGY AND CELL BIOLOGY | 2005年 / 83卷 / 03期

关键词：

epitope presentation; plant virus; polypeptide expression; viral vector;

D O I：

10.1111/j.1440-1711.2005.01339.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The small size of plant viral genomes, the ease with which they can be manipulated, and the simplicity of the infection process is making the viral vectors an attractive alternative to the transgenic systems for the expression of foreign proteins in plants. One use of these virus expression systems is for vaccine production. There are two basic types of viral system that have been developed for the production of immunogenic peptides and proteins in plants: epitope presentation and polypeptide expression systems. In this review, we discuss advances made in this field.

引用

页码：263 / 270

页数：8

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