Effect of flow baffles on the dialysate flow distribution of hollow-fiber hemodialyzers: A nonintrusive experimental study using MRI

被引：27

作者：

Poh, CK

Hardy, PA

Liao, ZJ

Huang, ZP

Clark, WR

Gao, DY ^{[1
]}

机构：

[1] Univ Kentucky, Dept Mech Engn, Lexington, KY 40506 USA

[2] Univ Kentucky, Ctr Biomed Engn, Lexington, KY 40506 USA

[3] Baxter Healthcare Corp, Rental Div, McGaw Pk, IL USA

来源：

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2003年 / 125卷 / 04期

关键词：

D O I：

10.1115/1.1590355

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We used an innovative, nonintrusive MRI technique called the two-dimensional (2D) Phase-Contrast (2DPC) velocity-imaging technique to investigate the effect of flow baffles on the dialysate-side flow distribution in two different hollow-fiber hemodialyzers (A and B); each with flow rates between 200 and 1000 mL/min (3.33X10(-6) and 1.67X10(-5) m(3)/s). Our experimental results show that (1) the dialysate-side flow distribution was nonuniform with channeling flow occurred at the peripheral cross section of these hollow-fiber hemodialyzers, and (2) the existing designs of flow baffles failed to promote uniform dialysate-side flow distribution for all flow rates studies.

引用

页码：481 / 489

页数：9

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