Efficient NMR pulse sequences to transfer the parahydrogen-induced polarization to hetero nuclei

被引：140

作者：

Haake, M ^{[1
]}

Natterer, J ^{[1
]}

Bargon, J ^{[1
]}

机构：

[1] UNIV BONN,INST PHYS CHEM,D-53115 BONN,GERMANY

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 36期

关键词：

D O I：

10.1021/ja960067f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The PASADENA or PHIP effect originates from the breakdown of the parahydrogen symmetry when the two protons are found in magnetically inequivalent positions after hydrogenation. As a result, a signal enhancement of up to 10(4) in the proton NMR spectra can be observed. We introduce three polarization transfer techniques, namely PH-INEPT, PH-INEPT+, and INEPT(+pi/4), that are highly effective to record in situ hetero NMR spectra of parahydrogen-labeled compounds. A complete product operator treatment as well as experimental results for C-13 and Si-29 have been given. With these sequences we obtained a signal enhancement of 500 which allows in situ NMR investigations of hetero nuclear systems at natural abundance.

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页码：8688 / 8691

页数：4

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