Exercise-induced stem cell activation and its implication for cardiovascular and skeletal muscle regeneration

被引:22
作者
Wahl, Patrick [1 ,2 ,3 ]
Brixius, Klara [2 ]
Bloch, Wilhelm [2 ]
机构
[1] German Sport Univ Cologne, Inst Training Sci & Sport Informat, D-50933 Cologne, Germany
[2] German Sport Univ Cologne, Inst Cardiovasc Res & Sport Med, Dept Mol & Cellular Sport Med, D-50933 Cologne, Germany
[3] German Sport Univ Cologne, German Res Ctr Elite Sports, D-50933 Cologne, Germany
关键词
exercise; stem cells; satellite cells; angiogenesis; VEGF;
D O I
10.1080/13645700801969816
中图分类号
R61 [外科手术学];
学科分类号
摘要
A number of publications have provided evidence that exercise and physical activity are linked to the activation, mobilization, and differentiation of various types of stem cells. Exercise may improve organ regeneration and function. This review summarizes mechanisms by which exercise contributes to stem cell-induced regeneration in the cardiovascular and the skeletal muscle system. In addition, it discusses whether exercise may improve and support stem cell transplantation in situations of cardiovascular disease or muscular dystrophy.
引用
收藏
页码:91 / 99
页数:9
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