Molecular understanding and modern application of traditional medicines: Triumphs and trials

被引：519

作者：

Corson, Timothy W.

Crews, Craig M. ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06511 USA

[2] Yale Univ, Dept Chem & Pharmacol, New Haven, CT 06511 USA

来源：

CELL | 2007年 / 130卷 / 05期

关键词：

D O I：

10.1016/j.cell.2007.08.021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Traditional medicines provide fertile ground for modern drug development, but first they must pass along a pathway of discovery, isolation, and mechanistic studies before eventual deployment in the clinic. Here, we highlight the challenges along this route, focusing on the compounds artemisinin, triptolide, celastrol, capsaicin, and curcumin.

引用

页码：769 / 774

页数：6

共 24 条

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