Role of CD8+ T lymphocytes in control of Mycobacterium tuberculosis infection

被引：116

作者：

Grotzke, JE

Lewinsohn, DM

机构：

[1] Oregon Hlth & Sci Univ, Dept Mol Microbiol & Immunol, Portland, OR 97239 USA

[2] Oregon Hlth & Sci Univ, Div Pulm & Crit Care Med, Portland VA Med Ctr, Portland, OR 97239 USA

来源：

MICROBES AND INFECTION | 2005年 / 7卷 / 04期

关键词：

tuberculosis; CD8-positive T-lymphocytes; antigen presentation; immunologic surveillance;

D O I：

10.1016/j.micinf.2005.03.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tuberculosis remains a global health concern. Control of infection is dependent on cell-mediated immune responses, with CD4(+) T lymphocytes playing a central role. In this article, data supporting the importance of CD8(+) T lymphocytes is reviewed, with an emphasis on the unique functional roles that this lymphocyte subset may play. (c) 2005 Elsevier SAS. All rights reserved.

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页码：776 / 788

页数：13

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