Addition reactions of O-bound cyclic nickel enolates to α,β-unsaturated ketones

被引：14

作者：

Cámpora, J

Maya, CM

Palma, P

Carmona, E

Graiff, C

Tiripicchio, A

机构：

[1] Univ Seville, CSIC, Inst Invest Quim, Seville 41092, Spain

[2] Univ Parma, Dipartimento Chim Gen & Inorgan, I-43100 Parma, Italy

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 14期

关键词：

D O I：

10.1039/b303062h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The addition of the O-bound nickel enolates Ni(C6H4-o-C(NCHR)O)(dippe) (R = H, 1; R = Me, 2) to alpha,beta-unsaturated ketones proceeds with complete stereoselectivity giving rise to [ 2 + 4] cycloadducts that can further evolve to generate open-chain, Michael-like products. The stereoselectivity of these reactions suggests a concerted mechanism, through an exo transition state.

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页码：1742 / 1743

页数：2

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