Two new aromatic constituents from the rootwood of Aeschynomene mimosifolia

被引：32

作者：

Fullas, F

Kornberg, LJ

Wani, MC

Wall, ME

Farnsworth, NR

Chagwedera, TE

Kinghorn, AD

机构：

[1] RES TRIANGLE INST,CHEM & LIFE SCI GRP,RES TRIANGLE PK,NC 27709

[2] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 02期

关键词：

D O I：

10.1021/np960052v

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The rootwood of Aeschynomene mimosifolia Vatke (Leguminosae) has yielded a new neoflavonoid, mimosifoliol (1), and an unusual C-16-styrylcycloheptenone derivative, mimoeifolenone (2). The structures of these compounds were determined on the basis of spectral analysis. Compound 1 demonstrated weak activity in DNA-strand scission assay, while compound 2 was found to be inactive. Mimosifoliol (1) was inactive toward several human cell lines, while 2 was moderately active against the KB cell line.

引用

页码：190 / 192

页数：3

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