Sequence variation: Looking for effects of genetic linkage

被引：25

作者：

Charlesworth, D ^{[1
]}

Charlesworth, B ^{[1
]}

机构：

[1] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 18期

关键词：

D O I：

10.1016/S0960-9822(07)00416-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Selection at linked loci probably reduces the variability of genes in regions of infrequent recombination. Detailed sequence information is needed to test possible causes of this effect; such information is now becoming available, but its interpretation can be difficult.

引用

页码：R658 / R661

页数：4

共 15 条

[1]

Aquadro Charles F., 1994, P46

[2] THE HITCHHIKING EFFECT ON THE SITE FREQUENCY-SPECTRUM OF DNA POLYMORPHISMS [J].

BRAVERMAN, JM ;

HUDSON, RR ;

KAPLAN, NL ;

LANGLEY, CH ;

STEPHAN, W .

GENETICS, 1995, 140 (02) :783-796

[3] Reductions in genetic variation in Drosophila and E-coli caused by selection at linked sites [J].

Charlesworth, B ;

Guttman, DS .

JOURNAL OF GENETICS, 1996, 75 (01) :49-61

[4]

CHARLESWORTH B, 1993, GENETICS, V134, P1289

[5]

CHARLESWORTH D, 1995, GENETICS, V141, P1619

[6] Nucleotide sequence diversity at the alcohol dehydrogenase 1 locus in wild barley (Hordeum vulgare ssp. spontaneum):: An evaluation of the background selection hypothesis [J].

Cummings, MP ;

Clegg, MT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (10) :5637-5642

[7]

Dvorák J, 1998, GENETICS, V148, P423

[8]

Gillespie John H., 1994, P1

[9] MOLECULAR EVIDENCE FOR NATURAL-SELECTION [J].

KREITMAN, M ;

AKASHI, H .

ANNUAL REVIEW OF ECOLOGY AND SYSTEMATICS, 1995, 26 :403-422

[10] Genetic diversity in Leavenworthia populations with different inbreeding levels [J].

Liu, F ;

Zhang, L ;

Charlesworth, D .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1998, 265 (1393) :293-301

← 1 2 →