A kinase to dampen the effects of cocaine?

被引：10

作者：

Gupta, A ^{[1
]}

Tsai, LH

机构：

[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[2] Howard Hughes Med Inst, Boston, MA 02115 USA

来源：

SCIENCE | 2001年 / 292卷 / 5515期

关键词：

D O I：

10.1126/science.1060028

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：236 / 237

页数：2

共 20 条

[1] Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons [J].

Bibb, JA ;

Snyder, GL ;

Nishi, A ;

Yan, Z ;

Meijer, L ;

Fienberg, AA ;

Tsai, LH ;

Kwon, YT ;

Girault, JA ;

Czernik, AJ ;

Huganir, RL ;

Hemmings, HC ;

Nairn, AC ;

Greengard, P .

NATURE, 1999, 402 (6762) :669-671

[2] Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 [J].

Bibb, JA ;

Chen, JS ;

Taylor, JR ;

Svenningsson, P ;

Nishi, A ;

Snyder, GL ;

Yan, Z ;

Sagawa, ZK ;

Ouimet, CC ;

Nairn, AC ;

Nestler, EJ ;

Greengard, P .

NATURE, 2001, 410 (6826) :376-380

[3]

BIBB JA, IN PRESS J BIOL CHEM

[4] Alzheimer's disease: Neurodevelopment converges with neurodegeneration [J].

Bothwell, M ;

Giniger, E .

CELL, 2000, 102 (03) :271-273

[5] Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality [J].

Chae, T ;

Kwon, YT ;

Bronson, R ;

Dikkes, P ;

Li, E ;

Tsai, LH .

NEURON, 1997, 18 (01) :29-42

[6]

Chen JS, 2000, J NEUROSCI, V20, P8965

[7] Beyond the dopamine receptor: the DARPP-32/Protein phosphatase-1 cascade [J].

Greengard, P ;

Allen, PB ;

Nairn, AC .

NEURON, 1999, 23 (03) :435-447

[8] RULES TO REPLICATE BY [J].

HEICHMAN, KA ;

ROBERTS, JM .

CELL, 1994, 79 (04) :557-562

[9] Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice [J].

Hiroi, N ;

Fienberg, AA ;

Haile, CN ;

Alburges, M ;

Hanson, GR ;

Greengard, P ;

Nestler, EJ .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1999, 11 (03) :1114-1118

[10] Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine [J].

Kelz, MB ;

Chen, JS ;

Carlezon, WA ;

Whisler, K ;

Gilden, L ;

Beckmann, AM ;

Steffen, C ;

Zhang, YJ ;

Marotti, L ;

Self, DW ;

Tkatch, T ;

Baranauskas, G ;

Surmeier, DJ ;

Neve, RL ;

Duman, RS ;

Picciotto, MR ;

Nestler, EJ .

NATURE, 1999, 401 (6750) :272-276

← 1 2 →