Activation of a consensus FNR-dependent promoter by DNR of Pseudomonas aeruginosa in response to nitrite

被引：15

作者：

Hasegawa, N

Arai, H

Igarashi, Y

机构：

[1] Univ Tokyo, Dept Biotechnol, Bunkyo Ku, Tokyo 1138657, Japan

[2] RIKEN, Inst Phys & Chem Res, Wako, Saitama 3510198, Japan

来源：

FEMS MICROBIOLOGY LETTERS | 1998年 / 166卷 / 02期

关键词：

denitrification; FNR; CRP; regulation : pseudomonas aeruginosa;

D O I：

10.1111/j.1574-6968.1998.tb13892.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Expression of the enzymes for anaerobic nitrate respiration of Pseudomonas aeruginosa requires two CRP/FNR-related transcriptional regulators, ANR and DNR. Activity of the consensus CRP- or FNR-dependent promoter in the anr and dnr deficient mutants was investigated. The CRP-dependent promoter was active in the mutant strains. Both regulators could activate the promoter with a consensus FNR-binding motif. DNR-dependent activation was nitrite-dependent, whereas activation by ANR was not, suggesting that only DNR is involved in sensing nitrogen oxides. (C) 1998 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

收藏

页码：213 / 217

页数：5

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