Genetics of melanoma predisposition

被引:26
作者
Lin, J. [1 ]
Hocker, T. L.
Singh, M.
Tsao, H. [2 ,3 ,4 ]
机构
[1] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[4] Massachusetts Gen Hosp, MGH Canc Ctr, Boston, MA 02114 USA
关键词
genetics; melanoma;
D O I
10.1111/j.1365-2133.2008.08682.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Over the past 10 years, our understanding of melanoma at the molecular level has blossomed with the advent of genomic technologies. The enormous enthusiasm for the Human Genome Project is slowly being replaced by an even greater excitement for the unravelling of disease genomes, including melanoma. In this review, we will consider some of the clinical implications of these genetic findings for both diagnostics and therapeutics.
引用
收藏
页码:286 / 291
页数:6
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