Angiogenesis inhibited by drinking tea

被引:545
作者
Cao, YH [1 ]
Cao, RH [1 ]
机构
[1] Karolinska Inst, Lab Angiogenesis Res, Ctr Microbiol & Tumor Biol, S-17177 Stockholm, Sweden
关键词
D O I
10.1038/18793
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Consumption of tea has been shown to inhibit the growth of several tumour types in animals, including cancers of the lung and oesophagus1,2,3. Drinking tea, especially green tea, is also associated with a lower incidence of human cancer1. The mechanisms of cancer inhibition are not known, although several hypotheses have been proposed. We investigated whether drinking green tea could suppress angiogenesis, a process of blood-vessel growth required for tumour growth and metastasis. We find that green tea, and one of its components, epigallocatechin-3-gallate (EGCG), significantly prevents the growth of new blood vessels in animals. This finding indicates that drinking tea may be beneficial for the prevention and treatment of angiogenesis-dependent diseases, including cancer and blindness caused by diabetes.
引用
收藏
页码:381 / 381
页数:1
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