Structure of the O-specific polysaccharide of Vibrio cholerae O9 containing 2-acetamido-2-deoxy-D-galacturonic acid

被引：7

作者：

Kocharova, NA

Knirel, YA

Jansson, PE ^{[1
]}

Weintraub, A

机构：

[1] Huddinge Univ Hosp, Karolinska Inst, Clin Res Ctr, Novum, S-14186 Huddinge, Sweden

[2] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow, Russia

[3] Huddinge Univ Hosp, Karolinska Inst, Dept Microbiol Pathol & Immunol, Div Clin Bacteriol, S-14186 Huddinge, Sweden

来源：

CARBOHYDRATE RESEARCH | 2001年 / 332卷 / 03期

关键词：

Vibrio cholerae; lipopolysaccharide; O-specific polysaccharide structures; 2-acetamido-2-deoxy-D-galacturonic acid;

D O I：

10.1016/S0008-6215(01)00069-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The O-specific polysaccharide (OPS) was isolated by mild-acid degradation of the lipopolysaccharide of Vibrio cholerae O9 and studied by carboxyl reduction, sugar and methylation analyses, Smith degradation, and two-dimensional NMR spectroscopy, including COSY, TOCSY, NOESY, and H-detected H-1,C-13 HMQC experiments. The following structure of the pentasaccharide-repeating unit of the OPS was established: [GRAPHICS] (C)2001 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：279 / 284

页数：6

相关论文

共 25 条

[1]

ALBERT MJ, 1993, LANCET, V342, P387, DOI 10.1016/0140-6736(93)92811-7

[2] EPIDEMIC OF DIARRHEA CAUSED BY VIBRIO-CHOLERAE NON-01 THAT PRODUCED HEAT-STABLE TOXIN AMONG KHMERS IN A CAMP IN THAILAND [J].

BAGCHI, K ;

ECHEVERRIA, P ;

ARTHUR, JD ;

SETHABUTR, O ;

SERICHANTALERGS, O ;

HOGE, CW .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (05) :1315-1317

[3] A high proportion of Vibrio cholerae strains isolated from children with diarrhoea in Bangkok, Thailand are multiple antibiotic resistant and belong to heterogenous non-O1, non-O139 O-serotypes [J].

Dalsgaard, A ;

Forslund, A ;

Bodhidatta, L ;

Serichantalergs, O ;

Pitarangsi, C ;

Pang, L ;

Shimada, T ;

Echeverria, P .

EPIDEMIOLOGY AND INFECTION, 1999, 122 (02) :217-226

[4] CHARACTERIZATION OF VIBRIO-CHOLERAE NON-O1 SEROGROUPS OBTAINED FROM AN OUTBREAK OF DIARRHEA IN LIMA, PERU [J].

DALSGAARD, A ;

ALBERT, MJ ;

TAYLOR, DN ;

SHIMADA, T ;

MEZA, R ;

SERICHANTALERGS, O ;

ECHEVERRIA, P .

JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (10) :2715-2722

[5] STUDIES OF THE STRUCTURE OF THE LIPOPOLY SACCHARIDE OF VIBRIO-ANGUILLARUM V-123 .2. STRUCTURE OF THE O-POLYSACCHARIDE CHAIN OF THE LIPOPOLYSACCHARIDE OF VIBRIO-ANGUILLARUM V-123 [J].

EGUCHI, H ;

KAYA, S ;

ARAKI, Y ;

KOJIMA, N ;

YOKOTA, S .

CARBOHYDRATE RESEARCH, 1992, 231 :159-169

[6] NON-01 VIBRIO-CHOLERAE INFECTIONS IN CANCUN, MEXICO [J].

FINCH, MJ ;

VALDESPINO, JL ;

WELLS, JG ;

PEREZPEREZ, G ;

ARJONA, F ;

SEPULVEDA, A ;

BESSUDO, D ;

BLAKE, PA .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1987, 36 (02) :393-397

[7]

HAKOMORI SI, 1964, J BIOCHEM-TOKYO, V55, P205

[8] Structural and serological characterisation of the O-antigenic polysaccharide of the lipopolysaccharide from Acinetobacter haemolyticus, strain ATCC 17906 [J].

Haseley, SR ;

Holst, O ;

Brade, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 244 (03) :761-766

[9] COMPUTER-ASSISTED STRUCTURAL-ANALYSIS OF POLYSACCHARIDES WITH AN EXTENDED VERSION OF CASPER USING H-1-NMR AND C-13-NMR DATA [J].

JANSSON, PE ;

KENNE, L ;

WIDMALM, G .

CARBOHYDRATE RESEARCH, 1989, 188 :169-191

[10]

Jansson PE, 1999, ENDOTOXIN IN HEALTH AND DISEASE, P155