Generation of functional diversity via nitroaldol condensations of alpha-aminoacid aldehydes - A new and stereocontrolled route to acyclic 1,3-diamino-2-alcohols

被引：51

作者：

Hanessian, S

Devasthale, PV

机构：

[1] Department of Chemistry, Université de Montréal, Montréal, Qué. H3C 3J7, P.O.Box 6128, Station Centre-ville

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 07期

关键词：

D O I：

10.1016/0040-4039(95)02359-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensations of N,N-dibenzyl alpha-amino aldehydes with nitroalkanes mediated by tetrabutylammonium fluoride proceed in excellent yields and selectivities. This affords rapid and stereoselective access to acyclic molecules containing differentiated nitrogen-containing functionality as well as diverse end groups.

引用

页码：987 / 990

页数：4

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