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Listeria as a vaccine vector

被引：64
作者：
Bruhn, Kevin W.
Craft, Noah
Miller, Jeff F.
机构：
[1] Univ Calif Los Angeles, Med Ctr, Los Angeles Biomed Res Inst, Dept Med,Div Dermatol, Torrance, CA 90502 USA
[2] Univ Calif Los Angeles, Inst Mol Biol, David Geffen Sch Med, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA
来源：
MICROBES AND INFECTION | 2007年 / 9卷 / 10期
关键词：
listeria monocytogenes; vaccine vector; cancer immunotherapy;
D O I：
10.1016/j.micinf.2007.05.010
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The immunostimulatory characteristics and intracellular niche of Listeria monocytogenes make it uniquely suitable for use as a live bacterial vaccine vector. Preclinical results supporting this idea, and current strategies to induce beneficial cell-mediated immunity to both infectious diseases and cancer with this vector, are discussed in this review. (C) 2007 Elsevier Masson SAS. All fights reserved.
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收藏
页码：1226 / 1235
页数：10
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