Temperature-responsive chromatography

被引：51

作者：

Kanazawa, H

Matsushima, Y

Okano, T

机构：

[1] Kyoritsu Coll Pharm, Minato Ku, Tokyo 105, Japan

[2] Tokyo Womens Med Coll, Inst Biomed Engn, Shinjuku Ku, Tokyo 162, Japan

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 1998年 / 17卷 / 07期

关键词：

temperature-responsive chromatography; poly(N-isopropylacrylamide); stationary phases; thermosensitive;

D O I：

10.1016/S0165-9936(98)00044-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We have developed a new method for HPLC which uses packing materials modified with a temperature-responsive polymer, poly(N-isopropylacrylamide). The surface properties and functions of the stationary phases are controlled by the external temperature. In the proposed chromatographic system, the elution of target substances is controlled by only a small change in the column temperatures. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：435 / 440

页数：6

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