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Malaria in Kenya's western highlands

被引：61
作者：
Shanks, GD
Hay, SI
Omumbo, JA
Snow, RW
机构：
[1] USA, Med Res Unit, Nairobi, Kenya
[2] Univ Oxford, Oxford, England
[3] Kenya Govt Med Res Ctr, Nairobi, Kenya
[4] John Radcliffe Hosp, Oxford OX3 9DU, England
来源：
EMERGING INFECTIOUS DISEASES | 2005年 / 11卷 / 09期
基金：
英国惠康基金;
关键词：
D O I：
10.3201/eid1109.041131
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Records from tea estates in the Kericho district in Kenya show that malaria reemerged in the 1980s. Renewed epidemic activity coincided with the emergence of chloroquine-resistant Plasmodium falciparum malaria and may have been triggered by the failure of antimalarial drugs. Meteorologic changes, population movements, degradation of health services, and changes in Anopheles vector populations are possible contributing factors. The highland malaria epidemics of the 1940s were stopped largely by sporontocidal drugs, and combination chemotherapy has recently limited transmission. Antimalarial drugs can limit the pool of gametocytes available to infect mosquitoes during the brief transmission season.
引用
收藏
页码：1425 / 1432
页数：8
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