On-line estimation of biomass concentration and non stationary parameters for aerobic bioprocesses

被引:14
作者
Lubenova, V
机构
[1] Bulgarian Academy of Sciences, Inst. Contr. Syst. Investigations, 1113 Sofia
关键词
adaptive estimation; biomass concentration; biomass growth rate; specific growth rate; aerobic bioprocess;
D O I
10.1016/0168-1656(95)00197-2
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The biomass concentration, a very important state variable of almost every bioprocess, cannot often be measured directly or estimated from related variables, such as the concentrations of substrates or products, due to the lack of reliable and cheap sensors. In this paper, a stable observer of biomass concentration is designed for those aerobic processes where the measurement of oxygen uptake rate is available on-line. This particular approach can also be applied for other reaction rates if the model of the process satisfies some very general assumptions, which make the dynamics of the biomass growth rate and the biomass concentration a linear function only of this unknown parameter and this state variable. With respect to a previous similar approach, the new observer has a different linear structure, which allows a simple tuning procedure. A comparison between the two different algorithms under similar conditions is realized.
引用
收藏
页码:197 / 207
页数:11
相关论文
共 14 条
[1]  
BASTIN G, 1989, ON LINE ESTIMATION A
[2]   MORPHOLOGY AND CLAVULANIC ACID PRODUCTION OF STREPTOMYCES-CLAVULIGERUS - EFFECT OF STIRRER SPEED IN BATCH FERMENTATIONS [J].
BELMARBEINY, MT ;
THOMAS, CR .
BIOTECHNOLOGY AND BIOENGINEERING, 1991, 37 (05) :456-462
[3]   NONLINEAR ESTIMATION OF SPECIFIC GROWTH-RATE FOR AEROBIC FERMENTATION PROCESSES [J].
CAZZADOR, L ;
LUBENOVA, V .
BIOTECHNOLOGY AND BIOENGINEERING, 1995, 47 (06) :626-632
[4]  
CAZZADOR L, 1995, 6 LADSEB CNR
[5]  
DOCHAIN D, 1986, THESIS U LOUVAIN LOU
[6]  
DOCHAIN D, 1993, P IMACS INT S MIM S, P34
[7]  
HOLMBERG A, 1982, AUTOMATICA, V18, P180
[8]  
Isermann R., 1981, DIGITAL CONTROL SYST
[9]  
LIM H, 1991, MEASURING MODELLING, P542
[10]  
LUBENOVA V, 1994, BIOPROCESS ENG, V11, P107