Deciphering the alphabet of G proteins: The structure of the alpha, beta, gamma heterotrimer

被引：9

作者：

Wittinghofer, A

机构：

[1] Max-Planck-Inst. F. Molec. Physiol., 44139 Dortmund

来源：

STRUCTURE | 1996年 / 4卷 / 04期

关键词：

D O I：

10.1016/S0969-2126(96)00040-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recent independent structure elucidations of two heterotrimeric G proteins represent a milestone in our understanding of the regulation of this important class of signal switch molecules. The results show how the introduction of GTP into the heterotrimer produces two signalling molecules: the G alpha-GTP and G beta,gamma subunits.

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收藏

页码：357 / 361

页数：5

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