An association between the kinship and fertility of human couples

被引：111

作者：

Helgason, Agnar ^{[1
,2
]}

Palsson, Snæbjoern ^{[1
,3
]}

Guobjartsson, Daniel F. ^{[1
]}

Kristjansson, Porour ^{[1
]}

Stefansson, Kari ^{[1
,4
]}

机构：

[1] deCODE Genet, IS-101 Reykjavik, Iceland

[2] Univ Iceland, Dept Anthropol, IS-101 Reykjavik, Iceland

[3] Univ Iceland, Dept Biol, IS-101 Reykjavik, Iceland

[4] Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland

来源：

SCIENCE | 2008年 / 319卷 / 5864期

关键词：

D O I：

10.1126/science.1150232

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Previous studies have reported that related human couples tend to produce more children than unrelated couples but have been unable to determine whether this difference is biological or stems from socioeconomic variables. Our results, drawn from all known couples of the Icelandic population born between 1800 and 1965, show a significant positive association between kinship and fertility, with the greatest reproductive success observed for couples related at the level of third and fourth cousins. Owing to the relative socioeconomic homogeneity of Icelanders, and the observation of highly significant differences in the fertility of couples separated by very fine intervals of kinship, we conclude that this association is likely to have a biological basis.

引用

页码：813 / 816

页数：4

共 15 条

[1]

AlHusain M, 1997, ANN TROP PAEDIATR, V17, P155

[2]

[Anonymous], 2006, Human Development Report

[3] Consanguinity and its relevance to clinical genetics [J].