Influence of continuous magnetic field on the separation of ephedrine enantiomers by molecularly imprinted polymers

被引:19
作者
Guerreiro, Antonio R. [1 ]
Korkhov, Vadim [2 ]
Mijangos, Irene [1 ]
Piletska, Elena V. [1 ]
Rodins, Juris [2 ]
Turner, Anthony P. F. [1 ]
Piletsky, Sergey A. [1 ]
机构
[1] Cranfield Univ, Silsoe MK45 4DT, Beds, England
[2] Latvian State Univ, Inst Polymer Mat, LV-1006 Riga, Latvia
关键词
molecularly imprinted polymers; magnetic field polymerisation;
D O I
10.1016/j.bios.2007.09.009
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A set of polymers was imprinted with (-)-ephedrine using UV initiation, under the influence of a constant external magnetic field with intensities ranging from 0 to 1.55T Synthesised materials were characterised by X-ray crystallography, infrared spectroscopy, swelling and surface area. Recognition properties were assessed by the ability to discriminate between (+) and (-)-ephedrine and by Scatchard analyses on chromatographic mode. It was shown that polymer morphology and recognition properties are affected by the magnetic field. This resulted in considerable improvements in the chromatographic resolution of ephedrine enantiomers by materials synthesised under the influence of magnetic field. Apparently the magnetic field improved the ordering of the polymer structure and facilitated the formation of more uniform imprinting sites. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:1189 / 1194
页数:6
相关论文
共 23 条
  • [1] Andersson HS, 1996, J MOL RECOGNIT, V9, P675, DOI 10.1002/(SICI)1099-1352(199634/12)9:5/6<675::AID-JMR320>3.0.CO
  • [2] 2-C
  • [3] Magnetic field orientation of liquid crystalline epoxy thermosets
    Benicewicz, BC
    Smith, ME
    Earls, JD
    Priester, RD
    Setz, SM
    Duran, RS
    Douglas, EP
    [J]. MACROMOLECULES, 1998, 31 (15) : 4730 - 4738
  • [4] Orientation of a longitudinal polymer liquid crystal in a constant magnetic field
    Brostow, W
    Faitelson, EA
    Kamensky, MG
    Korkhov, VP
    Rodin, YP
    [J]. POLYMER, 1999, 40 (06) : 1441 - 1449
  • [5] Quantification of active sites for the determination of methanol oxidation turn-over frequencies using methanol chemisorption and in situ infrared techniques. 2. Bulk metal oxide catalysts
    Burcham, LJ
    Briand, LE
    Wachs, IE
    [J]. LANGMUIR, 2001, 17 (20) : 6175 - 6184
  • [6] Testosterone receptor binding mimic constructed using molecular imprinting
    Cheong, SH
    McNiven, S
    Rachkov, K
    Levi, R
    Yano, K
    Karube, I
    [J]. MACROMOLECULES, 1997, 30 (05) : 1317 - 1322
  • [7] Polymerisation in a magnetic field 12. A comparative study regarding some properties of poly(acrylamide) synthesised in a magnetic field
    Chiriac, AP
    Neamtu, I
    Simionescu, CI
    [J]. POLYMER TESTING, 2000, 19 (04) : 405 - 413
  • [8] Magnetic field polymerisation
    Chiriac, AP
    Simionescu, CI
    [J]. PROGRESS IN POLYMER SCIENCE, 2000, 25 (02) : 219 - 258
  • [9] Dibiendu S B, 1998, POLYMER, V39, P525
  • [10] GUILDE A, 2001, ANAL CHEM, V73, P5596