Identification and characterization of the herpes simplex virus type 1 UL51 gene product

被引：38

作者：

Daikoku, T ^{[1
]}

Ikenoya, K ^{[1
]}

Yamada, H ^{[1
]}

Goshima, F ^{[1
]}

Nishiyama, Y ^{[1
]}

机构：

[1] Nagoya Univ, Sch Med, Dis Mechanism & Control Res Inst, Virol Lab,Showa Ku, Nagoya, Aichi 466, Japan

来源：

JOURNAL OF GENERAL VIROLOGY | 1998年 / 79卷

关键词：

D O I：

10.1099/0022-1317-79-12-3027

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The products of the herpes simplex virus type 1 UL51 gene were identified as phosphoproteins with apparent molecular masses of 27, 29 and 30 kDa. The proteins were produced at the late stage of infection, in a manner highly dependent on viral DNA synthesis, and were associated with extracellular virions. Immunofluorescence studies localized the UL51 proteins mainly to the cytoplasm, both in infected Vero cells and in transfected COS-1 cells singly expressing the UL51 gene.

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页码：3027 / 3031

页数：5

相关论文

共 15 条

[1] PRIMARY STRUCTURE OF THE HERPESVIRUS SAIMIRI GENOME [J].

ALBRECHT, JC ;

NICHOLAS, J ;

BILLER, D ;

CAMERON, KR ;

BIESINGER, B ;

NEWMAN, C ;

WITTMANN, S ;

CRAXTON, MA ;

COLEMAN, H ;

FLECKENSTEIN, B ;

HONESS, RW .

JOURNAL OF VIROLOGY, 1992, 66 (08) :5047-5058

[2] DNA-SEQUENCE AND EXPRESSION OF THE B95-8 EPSTEIN-BARR VIRUS GENOME [J].

BAER, R ;

BANKIER, AT ;

BIGGIN, MD ;

DEININGER, PL ;

FARRELL, PJ ;

GIBSON, TJ ;

HATFULL, G ;

HUDSON, GS ;

SATCHWELL, SC ;

SEGUIN, C ;

TUFFNELL, PS ;

BARRELL, BG .

NATURE, 1984, 310 (5974) :207-211

[3] IDENTIFICATION OF 3 GENES NONESSENTIAL FOR GROWTH IN CELL-CULTURE NEAR THE RIGHT TERMINUS OF THE UNIQUE SEQUENCES OF LONG COMPONENT OF HERPES-SIMPLEX VIRUS-1 [J].

BARKER, DE ;

ROIZMAN, B .

VIROLOGY, 1990, 177 (02) :684-691

[4] PSEUDORABIES VIRUS AND EQUINE HERPESVIRUS-1 SHARE A NONESSENTIAL GENE WHICH IS ABSENT IN OTHER HERPESVIRUSES AND LOCATED ADJACENT TO A HIGHLY CONSERVED GENE-CLUSTER [J].

BAUMEISTER, J ;

KLUPP, BG ;

METTENLEITER, TC .

JOURNAL OF VIROLOGY, 1995, 69 (09) :5560-5567

[5]

CHEE MS, 1990, CURR TOP MICROBIOL, V154, P125

[6] Purification and characterization of the protein kinase encoded by the UL13 gene of herpes simplex virus type 2 [J].

Daikoku, T ;

Shibata, S ;

Goshima, F ;

Oshima, S ;

Tsurumi, T ;

Yamada, H ;

Yamashita, Y ;

Nishiyama, Y .

VIROLOGY, 1997, 235 (01) :82-93

[7] THE COMPLETE DNA-SEQUENCE OF VARICELLA-ZOSTER VIRUS [J].

DAVISON, AJ ;

SCOTT, JE .

JOURNAL OF GENERAL VIROLOGY, 1986, 67 :1759-1816

[8] THE DNA-SEQUENCE OF HUMAN HERPESVIRUS-6 - STRUCTURE, CODING CONTENT, AND GENOME EVOLUTION [J].

GOMPELS, UA ;

NICHOLAS, J ;

LAWRENCE, G ;

JONES, M ;

JONES, M ;

THOMSON, BJ ;

MARTIN, MED ;

EFSTATHIOU, S ;

CRAXTON, M ;

MACAULAY, HA .

VIROLOGY, 1995, 209 (01) :29-51

[9] The pseudorabies virus UL51 gene product is a 30-kilodalton virion component [J].

Lenk, M ;

Visser, N ;

Mettenleiter, TC .

JOURNAL OF VIROLOGY, 1997, 71 (07) :5635-5638

[10] THE COMPLETE DNA-SEQUENCE OF THE LONG UNIQUE REGION IN THE GENOME OF HERPES-SIMPLEX VIRUS TYPE-1 [J].

MCGEOCH, DJ ;

DALRYMPLE, MA ;

DAVISON, AJ ;

DOLAN, A ;

FRAME, MC ;

MCNAB, D ;

PERRY, LJ ;

SCOTT, JE ;

TAYLOR, P .

JOURNAL OF GENERAL VIROLOGY, 1988, 69 :1531-1574