Brasiliquinones A-C, new cytotoxic benz[a]anthraquinones with an ethyl group at C-3 from actinomycete Nocardia brasiliensis

被引:30
作者
Tsuda, M
Sato, H
Tanaka, Y
Yazawa, G
Mikami, Y
Sasaki, T
Kobayashi, J
机构
[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN
[2] CHIBA UNIV,PATHOGEN FUNGI & MICROBIAL TOXICOSES RES CTR,CHIBA 280,JAPAN
[3] KANAZAWA UNIV,CANC RES INST,KANAZAWA,ISHIKAWA 920,JAPAN
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 15期
关键词
D O I
10.1039/p19960001773
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new cytotoxic benz[a]anthraquinones with an ethyl group at C-3, brasiliquinones A-C 1-3, have been isolated from the actinomycete Nocardia brasiliensis IFM 0089, and their structures elucidated on the basis of spectroscopic data and by chemical means, Brasiliquinone A 1 is the first benz[a]anthraquinone possessing ristosamine as an O-glycoside moiety, while brasiliquinones B 2 and C 3 correspond to the aglycone of 1 and the 8-O-methyl derivative of 2, respectively.
引用
收藏
页码:1773 / 1775
页数:3
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