Pegylated interferon and ribavirin-induced interstitial pneumonitis with ARDS

被引：40

作者：

Abi-Nassif, S

Mark, EJ

Fogel, RB

Hallisey, RK

机构：

[1] MGH, Dept Pharm, Boston, MA 02114 USA

[2] MGH, Dept Med, Boston, MA 02114 USA

[3] MGH, Div Pulm & Crit Care, Boston, MA 02114 USA

[4] MGH, Dept Pathol, Boston, MA 02114 USA

来源：

CHEST | 2003年 / 124卷 / 01期

关键词：

ARDS; interferon-alpha; interstitial lung disease;

D O I：

10.1378/chest.124.1.406

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 49-year-old man with cirrhosis due to hepatitis C virus developed interstitial pneumonitis documented by surgical lung biopsy specimen evaluation after two weekly doses of pegylated interferon-alpha(2)b in combination with ribavirin. He developed ARDS and died after 26 days of hospitalization from multisystem organ failure. This case suggests that interstitial pulmonary disease can occur with pegylated interferon-alpha(2)b therapy.

引用

收藏

页码：406 / 410

页数：5

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