New model to characterise cell-substrate adhesion in the presence of osmosis

被引：18

作者：

Liu, KK ^{[1
]}

Wan, KT ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Mech & Prod Engn, Singapore 2263, Singapore

来源：

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING | 2000年 / 38卷 / 06期

关键词：

cell adhesion; adhesive contact; adhesion strength; membrane elasticity; cell mechanics; osmotic swelling;

D O I：

10.1007/BF02344877

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

A simple model of cell-substrate adhesion, in response to osmosis change, is derived to describe quantitatively the interrelationships between osmotic inflation, contact area and angle, membrane stretching and adhesion strength. As the cell inflates, the contact area shrinks in dimension, until the cell is eventually lifted off the substrate. The theoretical prediction is consistent with other published data.

引用

页码：690 / 691

页数：2

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