Systemic antifungal prophylaxis for very low birthweight infants: a systematic review

被引:18
作者
Clerihew, L. [1 ]
Austin, N. [2 ]
McGuire, W. [3 ]
机构
[1] Ninewells Hosp & Med Sch, Dundee, Scotland
[2] Christchurch Womens Hosp, Christchurch, New Zealand
[3] Australian Natl Univ, Canberra, ACT, Australia
来源
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 2008年 / 93卷 / 03期
关键词
D O I
10.1136/adc.2007.121962
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Systematic review and meta-analysis of four randomised controlled trials suggest that prophylactic fluconazole reduces the incidence of invasive fungal infection in very low birthweight infants. Further trials are needed to provide more precise estimates of effect size, and to assess the effect on mortality, neurodevelopment and the emergence of antifungal resistance.
引用
收藏
页码:F198 / F200
页数:3
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