The diverse roles of ubiquitin and the 26S proteasome in the life of plants

被引:183
作者
Sullivan, JA
Shirasu, K
Deng, XW
机构
[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
[2] John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England
基金
美国国家科学基金会; 英国生物技术与生命科学研究理事会; 美国国家卫生研究院;
关键词
D O I
10.1038/nrg1228
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A tightly regulated and highly specific system for the degradation of individual proteins is essential for the survival of all organisms. In eukaryotes, this is achieved by the tagging of proteins with ubiquitin and their subsequent recognition and degradation by the 26S proteasome. In plants, genetic analysis has identified many genes that regulate developmental pathways. Subsequent analysis of these genes has implicated ubiquitin and the 26S proteasome in the control of diverse developmental processes, and indicates that proteolysis is a crucial regulatory step throughout the life cycle of plants.
引用
收藏
页码:948 / 958
页数:11
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