A 37-year-old spinal cord-injured female patient, transplanted of multipotent stem cells from human UC blood, with improved sensory perception and mobility, both functionally and morphologically: a case study

被引:133
作者
Kang, KS
Kim, SW
Oh, YH
Yu, JW
Kim, KY
Park, HK
Song, CH
Han, H
机构
[1] Seoul Natl Univ, Coll Vet Med, Lab Stem Cell & Tumor Biol, Seoul, South Korea
[2] Histostem Co, Seoul Cord Blood Bank, Seoul, South Korea
[3] New Life Clin, Seoul, South Korea
[4] Chosun Univ Hosp, Kwangju, South Korea
[5] Hanyang Univ, Coll Med, Dept Surg, Seoul 133791, South Korea
关键词
clinical trial; multipotent stem cells; spinal cord injury; UC blood;
D O I
10.1080/14653240500238160
中图分类号
Q813 [细胞工程];
学科分类号
摘要
HLA-matched UC blood-derived multipotent stem cells were directly transplanted into the injured spinal cord site of a 37-year-old female patient suffering from spinal cord injury (SPI). In this case, human cord blood (UCB)-derived multipotent stem cells improved sensory perception and movement in the SPI patient's hips and thighs within 41 days of cell transplantation. CT and MRI results also showed regeneration of the spinal cord at the injured site and some of the cauda equina below it. Therefore, it is suggested that UCB multipotent stem cell transplantation could be a good treatment method for SPI patients.
引用
收藏
页码:368 / 373
页数:6
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