Unresectable primary tumor of head and neck: Does neck dissection combined with chemoradiotherapy improve survival?

被引:22
作者
Carinci, F
Cassano, L
Farina, A
Pelucchi, S
Calearo, C
Modugno, V
Nielsen, I
Api, P
Pastore, A
机构
[1] Univ Ferrara, Arcispedale S Anna, ENT Clin, I-44100 Ferrara, Italy
[2] Univ Bologna, Inst Histol, I-40126 Bologna, Italy
[3] Arcispedale St Anna, Dept Oncol, Ferrara, Italy
[4] Arcispedale St Anna, Dept Radiol, Ferrara, Italy
关键词
head and neck; unresectable tumor; squamous cell carcinoma; survival; chemotherapy; radiotherapy; neck dissection;
D O I
10.1097/00001665-200109000-00007
中图分类号
R61 [外科手术学];
学科分类号
摘要
A study regarding patients with primary and previously untreated advanced histologically proven squamous cell carcinoma of the head and neck was performed to compare two treatment modalities: neck dissection followed by chemoradiotherapy (Group I) versus chemoradiotherapy alone (Group II). Fifty-four patients were randomly chosen to receive Group I or II treatment. Our results demonstrate that Group I treatment has a higher and statistically significant disease-specific survival rate. We suggest that an association of neck dissection plus chemoradiotherapy can be useful in the event of unresectable advanced carcinomas.
引用
收藏
页码:438 / 443
页数:6
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