Near-infrared reflectance spectrometry in the study of atopy .2. Interactions between the skin and polyethylene glycol 400, isopropyl myristate and hydrogel

被引:5
作者
Dreassi, E
Ceramelli, G
Mura, P
Perruccio, PL
Vocioni, F
Bartalini, P
Corti, P
机构
[1] UNIV FLORENCE,DEPT PHARMACOL SCI,I-50121 FLORENCE,ITALY
[2] MIL PHARMACEUT ESTAB,I-50144 FLORENCE,ITALY
[3] UNIV SIENA,DERMATOL CLIN,I-53100 SIENA,ITALY
关键词
near-infrared spectrometry; atopy; skin; polyethylene glycol 400; isopropyl myristate; hydrogel;
D O I
10.1039/a701257h
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An investigation into the existence of spectral differences and differences in response in terms of water and lipid content between normal and atopic skin after interaction with chemical agents is described, Three compounds were taken as models: a prevalently hydrophilic solvent (polyethylene glycol, PEG 400), a prevalently lipophilic solvent (isopropyl myristate) and a hydrophilic pharmaceutical (gel) used to promote contact in electrocardiography, Using principal component analysis it was possible to distinguish atopic and normal subjects by simple contact of the skin with chemical agents.
引用
收藏
页码:771 / 776
页数:6
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