The development of vaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus

被引：171

作者：

Newton, SE

Munn, EA

机构：

[1] Victorian Inst Anim Sci, Attwood, Vic 3049, Australia

[2] Babraham Inst, Dept Immunol, Cambridge CB2 4AT, England

来源：

PARASITOLOGY TODAY | 1999年 / 15卷 / 03期

关键词：

D O I：

10.1016/S0169-4758(99)01399-X

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Many parasitic nematodes are developing resistance to chemical treatment, and the search is on to produce commercially viable molecular vaccines. Much progress has been made with highly protective 'hidden antigens' especially for Haemonchus contort-us, nod recent work with new 'natural antigens' has yielded promising results. Here, Sue Newton and Ed Munn review the most recent advances in these two main approaches to this problem.

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页码：116 / 122

页数：7

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