Heme oxygenase-1 in renal injury: Conclusions of studies in humans and animal models

被引:27
作者
Kanwar, YS [1 ]
机构
[1] Northwestern Univ, Sch Med, Dept Pathol, Chicago, IL 60611 USA
关键词
nuclear factor-kappa B (NF-kappa B) heme proteins; tubulointerstitial injury; fibrogenic cytokines inflammatory response; monocyte chemoattractant peptide (MCP-1);
D O I
10.1046/j.1523-1755.2001.00505.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:378 / 379
页数:2
相关论文
共 19 条
[1]  
Agarwal A, 2000, J AM SOC NEPHROL, V11, P965, DOI 10.1681/ASN.V115965
[2]   Heme oxygenase-1 in tissue pathology -: The yin and yang [J].
Dong, Z ;
Lavrovsky, Y ;
Venkatachalam, MA ;
Roy, AK .
AMERICAN JOURNAL OF PATHOLOGY, 2000, 156 (05) :1485-1488
[3]   Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes [J].
Hancock, WW ;
Buelow, R ;
Sayegh, MH ;
Turka, LA .
NATURE MEDICINE, 1998, 4 (12) :1392-1396
[4]   Renal response to repetitive exposure to heme proteins: Chronic injury induced by an acute insult [J].
Nath, KA ;
Croatt, AJ ;
Haggard, JJ ;
Grande, JP .
KIDNEY INTERNATIONAL, 2000, 57 (06) :2423-2433
[5]   The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo [J].
Nath, KA ;
Haggard, JJ ;
Croatt, AJ ;
Grande, JP ;
Poss, KD ;
Alam, J .
AMERICAN JOURNAL OF PATHOLOGY, 2000, 156 (05) :1527-1535
[6]   Heme oxygenase-1: a redoubtable response that limits reperfusion injury in the transplanted adipose liver [J].
Nath, KA .
JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (11) :1485-1486
[7]   Intracellular targets in heme protein-induced renal injury [J].
Nath, KA ;
Grande, JP ;
Croatt, AJ ;
Likely, S ;
Hebbel, RP ;
Enright, H .
KIDNEY INTERNATIONAL, 1998, 53 (01) :100-111
[8]  
NATH KA, 1992, AM J KIDNEY DIS, V20, P1
[9]   Heme protein-induced chronic renal inflammation: Suppressive effect of induced heme oxygenase-1 [J].
Nath, KA ;
Vercellotti, GM ;
Grande, JP ;
Miyoshi, H ;
Paya, CV ;
Manivel, JC ;
Haggard, JJ ;
Croatt, AJ ;
Payne, WD ;
Alam, J .
KIDNEY INTERNATIONAL, 2001, 59 (01) :106-117
[10]   HEME PROTEIN-MEDIATED RENAL INJURY - A PROTECTIVE ROLE FOR 21-AMINOSTEROIDS IN-VITRO AND IN-VIVO [J].
NATH, KA ;
BALLA, J ;
CROATT, AJ ;
VERCELLOTTI, GM .
KIDNEY INTERNATIONAL, 1995, 47 (02) :592-602