Microrheology of entangled F-actin solutions

被引：265

作者：

Gardel, ML ^{[1
]}

Valentine, MT

Crocker, JC

Bausch, AR

Weitz, DA

机构：

[1] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA

[2] Harvard Univ, DEAS, Cambridge, MA 02138 USA

[3] Univ Penn, Dept Chem & Biomol Engn, Philadelphia, PA 19104 USA

[4] Tech Univ Munich, Lehrstuhl Biophys E22, D-8046 Garching, Germany

来源：

PHYSICAL REVIEW LETTERS | 2003年 / 91卷 / 15期

关键词：

D O I：

10.1103/PhysRevLett.91.158302

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We measure the viscoelasticity of entangled F-actin over length scales between 1 and 100 mum using one- and two-particle microrheology, and directly identify two distinct microscopic contributions to the elasticity. Filament entanglements lead to a frequency-independent elastic modulus over an extended frequency range of 0.01-30 rad/sec; this is probed with one-particle microrheology. Longitudinal fluctuations of the filaments increase the elastic modulus between 0.1 and 30 rad/sec at length scales up to the filament persistence length; this is probed by two-particle microrheology.

引用

页数：4

共 24 条

[1]

ALBERTS B, 1989, ESSENTIAL CELL BIOL

[2] Subdiffusion and anomalous local viscoelasticity in actin networks [J].